Goat Secondary Antibodies
ABclonal Technology CALM3 Rabbit pAb
This gene encodes a member of a family of proteins that binds calcium and functions as a enzymatic co-factor. Activity of this protein is important in the regulation of the cell cycle and cytokinesis. Multiple alternatively spliced transcript variants have been observed at this gene.
ABclonal Technology Moesin Rabbit pAb
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.
Cayman Chemical TetrachlorohydroquInon 5g
A metabolite of pentachlorophenol; cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay); increases production of ROS, inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes; induces GSH depletion in mouse liver
Cayman Chemical -ProprnololhydrochlorId 25g
A β-adrenergic receptor antagonist (Kds = 6.91, 0.832, and 117.49 nM for human β1-, β2-, and β3-ARs, respectively); reduces mean blood pressure, resting heart rate, and contractility and increases AV conduction time in dogs; restores normal sinus rhythm in dogs with ouabain-induced arrhythmias (ED50 = 3.8 mg/kg); acts as a non-specific serotonin receptor antagonist, reducing tranylcypromine/L-tryptophan-induced hyperactivity in rats
ABclonal Technology IGFBP5 Rabbit pAb
Enables insulin-like growth factor I binding activity. Involved in several processes, including cellular response to cAMP, regulation of smooth muscle cell migration, and regulation of smooth muscle cell proliferation. Part of insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis.
Cayman Chemical LInoelaIdIc AcId 5g
Linoelaidic acid is the all-trans fatty acid homolog of linoleic acid. Trans-fatty acids are generally not detected in raw food oils, but constitute up to 25% of the unsaturated fat in partially hydrogenated oils.{5470}
ABclonal Technology eIF4EBP1 Rabbit pAb
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
ABclonal Technology CDK5RAP3 Rabbit pAb
This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms.
Cayman Chemical THUNDRPhosphoInsulIn Rece 96
Sandwich TR-FRET immunoassay for semi-quantitative detection of Phospho-Insulin Receptor β (Y1150/Y1151) in cell lysates
ABclonal Technology 647 anti-Human OPN1LW/OPN1MW
This gene encodes a light-absorbing visual pigment known as red cone photopigment or long-wavelength sensitive opsin part of the opsin gene family Opsins are G-protein coupled receptors with seven transmembrane domains an N-terminal extracellular domain and a C-terminal cytoplasmic domain This gene along with the medium-wavelength opsin gene is tandemly located on the X chromosome where unequal recombination and gene conversion can occur leading to fusions or multiple gene copies Defects in this gene cause partial protanopic color blindness The medium-wavelength opsin gene is similarly involved in deutanopic color blindness
Bio X Cell Anti-Human IgE, Omalizumab Biosimilar, Unconjugated, 100 MG
This non-therapeutic biosimilar antibody utilizes the same variable regions as the therapeutic antibody Omalizumab, making it suitable for research applications. It reacts with free human IgE in blood and interstitial fluid, and with membrane-bound IgE on IgE-expressing B cells. It does not bind to IgE complexed with FcεRI and does not induce histamine release.
- Target human IgE
- Human species reactivity
- Unconjugated
- Human IgG1, κ isotype
- Immunogen human IgE
- Purity ≥95% by SDS-PAGE
- Endotoxin ≤0.5EU/mg by LAL assay
- Molecular weight 150 kDa
- Formulation PBS, pH 7.0, no stabilizers or preservatives
- Store at 4°C, do not freeze
- Applications: IgE neutralization, flow cytometry, ELISA
- Purification by protein A
- Sterility by 0.2 μm filtration
ABclonal Technology KCNJ2 Rabbit pAb
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.
Cayman Chemical PPARLBD LIgnd Screeng384
A growth hormone secretagogue and ghrelin receptor agonist binds to GHS-R1a (IC50 123 nM for the human receptor) oral administration increases plasma growth hormone levels in dogs at 1 mg/kg decreases gastric acid secretion in pylorus-ligated rats at 0.01 or 1 nmol/animal i.c.v. increases acute food intake and body weight in mice at 10 mg/kg decreases the number and total duration of seizures in mice induced with dopamine D1 receptor kindling using SKF 81297
Cayman Chemical DracorhodIn Perchlorate 250mg
A pro-apoptotic compound and a synthetic analog of dracorhodin; cytotoxic to U937, A375-S2, and MCF-7 cells in a concentration-dependent manner; cytotoxic to HeLa cells, an effect that can be reversed by Ac-YVAD-CMK, A-DEVD-FMK, Z-IETD-FMK, and Z-LEHD-FMK, which are inhibitors of caspase-1, -3, -8, and -9, respectively